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hbv capture sequencing  (MyGenostics Inc)

 
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    MyGenostics Inc hbv capture sequencing
    A Map of the CCDC91 gene with <t>HBV</t> DNA insertion in HCC (n = 17) and NHL (n = 1) tissues. Black arrows indicate HBV integration sites identified through pooled-analysis in HCC. Red arrows represent HBV integration sites detected in HCC samples using our HBV capture <t>sequencing</t> approach. Blue arrows denote HBV integration sites identified in non-Hodgkin lymphoma (NHL) samples from our previous HBV capture sequencing study. B Immunohistochemistry staining showed the protein expression of CCDC91 in 4 HBV capture sequencing HCC tissues. C The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from GSEA cohorts ( GSE36376 : n = 193 in non-tumor, n = 240 in tumor; GSE76427 : n = 52 in non-tumor, n = 115 in tumor). D The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from TCGA cohort (n = 50 in non-tumor, n = 371 in tumor). E Relative mRNA levels of CCDC91 in HCC cells as determined by qPCR (n = 3 independent biological repeats). F Representative IHC images of CCDC91 in HCC tissues and adjacent paratumor tissues (left) and IHC scores of CCDC91 staining in HCC tissues and non-cancerous liver tissues (right, n = 123). G The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TCGA dataset. H Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TCGA dataset (n = 240). I Multivariate Cox regression analysis of the data from the TCGA dataset revealed that CCDC91 was an independent predictor of OS (n = 120). J The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TMA cohort (n = 123). K Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TMA cohort (n = 80). Statistical analysis was performed using Student’s t test in ( C , D , E , and F ). Error bars represent the SEM. *, p < 0.05; **, p < 0.01; ***, p < 0.001.
    Hbv Capture Sequencing, supplied by MyGenostics Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/hbv capture sequencing/product/MyGenostics Inc
    Average 90 stars, based on 1 article reviews
    hbv capture sequencing - by Bioz Stars, 2026-03
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    1) Product Images from "HBV DNA integration gene CCDC91 is oncogenic and a potential therapeutic target for hepatocellular carcinoma"

    Article Title: HBV DNA integration gene CCDC91 is oncogenic and a potential therapeutic target for hepatocellular carcinoma

    Journal: Communications Biology

    doi: 10.1038/s42003-025-08369-1

    A Map of the CCDC91 gene with HBV DNA insertion in HCC (n = 17) and NHL (n = 1) tissues. Black arrows indicate HBV integration sites identified through pooled-analysis in HCC. Red arrows represent HBV integration sites detected in HCC samples using our HBV capture sequencing approach. Blue arrows denote HBV integration sites identified in non-Hodgkin lymphoma (NHL) samples from our previous HBV capture sequencing study. B Immunohistochemistry staining showed the protein expression of CCDC91 in 4 HBV capture sequencing HCC tissues. C The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from GSEA cohorts ( GSE36376 : n = 193 in non-tumor, n = 240 in tumor; GSE76427 : n = 52 in non-tumor, n = 115 in tumor). D The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from TCGA cohort (n = 50 in non-tumor, n = 371 in tumor). E Relative mRNA levels of CCDC91 in HCC cells as determined by qPCR (n = 3 independent biological repeats). F Representative IHC images of CCDC91 in HCC tissues and adjacent paratumor tissues (left) and IHC scores of CCDC91 staining in HCC tissues and non-cancerous liver tissues (right, n = 123). G The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TCGA dataset. H Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TCGA dataset (n = 240). I Multivariate Cox regression analysis of the data from the TCGA dataset revealed that CCDC91 was an independent predictor of OS (n = 120). J The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TMA cohort (n = 123). K Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TMA cohort (n = 80). Statistical analysis was performed using Student’s t test in ( C , D , E , and F ). Error bars represent the SEM. *, p < 0.05; **, p < 0.01; ***, p < 0.001.
    Figure Legend Snippet: A Map of the CCDC91 gene with HBV DNA insertion in HCC (n = 17) and NHL (n = 1) tissues. Black arrows indicate HBV integration sites identified through pooled-analysis in HCC. Red arrows represent HBV integration sites detected in HCC samples using our HBV capture sequencing approach. Blue arrows denote HBV integration sites identified in non-Hodgkin lymphoma (NHL) samples from our previous HBV capture sequencing study. B Immunohistochemistry staining showed the protein expression of CCDC91 in 4 HBV capture sequencing HCC tissues. C The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from GSEA cohorts ( GSE36376 : n = 193 in non-tumor, n = 240 in tumor; GSE76427 : n = 52 in non-tumor, n = 115 in tumor). D The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from TCGA cohort (n = 50 in non-tumor, n = 371 in tumor). E Relative mRNA levels of CCDC91 in HCC cells as determined by qPCR (n = 3 independent biological repeats). F Representative IHC images of CCDC91 in HCC tissues and adjacent paratumor tissues (left) and IHC scores of CCDC91 staining in HCC tissues and non-cancerous liver tissues (right, n = 123). G The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TCGA dataset. H Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TCGA dataset (n = 240). I Multivariate Cox regression analysis of the data from the TCGA dataset revealed that CCDC91 was an independent predictor of OS (n = 120). J The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TMA cohort (n = 123). K Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TMA cohort (n = 80). Statistical analysis was performed using Student’s t test in ( C , D , E , and F ). Error bars represent the SEM. *, p < 0.05; **, p < 0.01; ***, p < 0.001.

    Techniques Used: Sequencing, Immunohistochemistry, Staining, Expressing



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    A Map of the CCDC91 gene with <t>HBV</t> DNA insertion in HCC (n = 17) and NHL (n = 1) tissues. Black arrows indicate HBV integration sites identified through pooled-analysis in HCC. Red arrows represent HBV integration sites detected in HCC samples using our HBV capture <t>sequencing</t> approach. Blue arrows denote HBV integration sites identified in non-Hodgkin lymphoma (NHL) samples from our previous HBV capture sequencing study. B Immunohistochemistry staining showed the protein expression of CCDC91 in 4 HBV capture sequencing HCC tissues. C The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from GSEA cohorts ( GSE36376 : n = 193 in non-tumor, n = 240 in tumor; GSE76427 : n = 52 in non-tumor, n = 115 in tumor). D The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from TCGA cohort (n = 50 in non-tumor, n = 371 in tumor). E Relative mRNA levels of CCDC91 in HCC cells as determined by qPCR (n = 3 independent biological repeats). F Representative IHC images of CCDC91 in HCC tissues and adjacent paratumor tissues (left) and IHC scores of CCDC91 staining in HCC tissues and non-cancerous liver tissues (right, n = 123). G The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TCGA dataset. H Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TCGA dataset (n = 240). I Multivariate Cox regression analysis of the data from the TCGA dataset revealed that CCDC91 was an independent predictor of OS (n = 120). J The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TMA cohort (n = 123). K Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TMA cohort (n = 80). Statistical analysis was performed using Student’s t test in ( C , D , E , and F ). Error bars represent the SEM. *, p < 0.05; **, p < 0.01; ***, p < 0.001.
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    A Map of the CCDC91 gene with <t>HBV</t> DNA insertion in HCC (n = 17) and NHL (n = 1) tissues. Black arrows indicate HBV integration sites identified through pooled-analysis in HCC. Red arrows represent HBV integration sites detected in HCC samples using our HBV capture <t>sequencing</t> approach. Blue arrows denote HBV integration sites identified in non-Hodgkin lymphoma (NHL) samples from our previous HBV capture sequencing study. B Immunohistochemistry staining showed the protein expression of CCDC91 in 4 HBV capture sequencing HCC tissues. C The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from GSEA cohorts ( GSE36376 : n = 193 in non-tumor, n = 240 in tumor; GSE76427 : n = 52 in non-tumor, n = 115 in tumor). D The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from TCGA cohort (n = 50 in non-tumor, n = 371 in tumor). E Relative mRNA levels of CCDC91 in HCC cells as determined by qPCR (n = 3 independent biological repeats). F Representative IHC images of CCDC91 in HCC tissues and adjacent paratumor tissues (left) and IHC scores of CCDC91 staining in HCC tissues and non-cancerous liver tissues (right, n = 123). G The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TCGA dataset. H Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TCGA dataset (n = 240). I Multivariate Cox regression analysis of the data from the TCGA dataset revealed that CCDC91 was an independent predictor of OS (n = 120). J The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TMA cohort (n = 123). K Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TMA cohort (n = 80). Statistical analysis was performed using Student’s t test in ( C , D , E , and F ). Error bars represent the SEM. *, p < 0.05; **, p < 0.01; ***, p < 0.001.
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    Image Search Results


    A Map of the CCDC91 gene with HBV DNA insertion in HCC (n = 17) and NHL (n = 1) tissues. Black arrows indicate HBV integration sites identified through pooled-analysis in HCC. Red arrows represent HBV integration sites detected in HCC samples using our HBV capture sequencing approach. Blue arrows denote HBV integration sites identified in non-Hodgkin lymphoma (NHL) samples from our previous HBV capture sequencing study. B Immunohistochemistry staining showed the protein expression of CCDC91 in 4 HBV capture sequencing HCC tissues. C The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from GSEA cohorts ( GSE36376 : n = 193 in non-tumor, n = 240 in tumor; GSE76427 : n = 52 in non-tumor, n = 115 in tumor). D The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from TCGA cohort (n = 50 in non-tumor, n = 371 in tumor). E Relative mRNA levels of CCDC91 in HCC cells as determined by qPCR (n = 3 independent biological repeats). F Representative IHC images of CCDC91 in HCC tissues and adjacent paratumor tissues (left) and IHC scores of CCDC91 staining in HCC tissues and non-cancerous liver tissues (right, n = 123). G The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TCGA dataset. H Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TCGA dataset (n = 240). I Multivariate Cox regression analysis of the data from the TCGA dataset revealed that CCDC91 was an independent predictor of OS (n = 120). J The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TMA cohort (n = 123). K Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TMA cohort (n = 80). Statistical analysis was performed using Student’s t test in ( C , D , E , and F ). Error bars represent the SEM. *, p < 0.05; **, p < 0.01; ***, p < 0.001.

    Journal: Communications Biology

    Article Title: HBV DNA integration gene CCDC91 is oncogenic and a potential therapeutic target for hepatocellular carcinoma

    doi: 10.1038/s42003-025-08369-1

    Figure Lengend Snippet: A Map of the CCDC91 gene with HBV DNA insertion in HCC (n = 17) and NHL (n = 1) tissues. Black arrows indicate HBV integration sites identified through pooled-analysis in HCC. Red arrows represent HBV integration sites detected in HCC samples using our HBV capture sequencing approach. Blue arrows denote HBV integration sites identified in non-Hodgkin lymphoma (NHL) samples from our previous HBV capture sequencing study. B Immunohistochemistry staining showed the protein expression of CCDC91 in 4 HBV capture sequencing HCC tissues. C The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from GSEA cohorts ( GSE36376 : n = 193 in non-tumor, n = 240 in tumor; GSE76427 : n = 52 in non-tumor, n = 115 in tumor). D The mRNA levels of CCDC91 in HCC tissues and non-cancerous liver tissues from TCGA cohort (n = 50 in non-tumor, n = 371 in tumor). E Relative mRNA levels of CCDC91 in HCC cells as determined by qPCR (n = 3 independent biological repeats). F Representative IHC images of CCDC91 in HCC tissues and adjacent paratumor tissues (left) and IHC scores of CCDC91 staining in HCC tissues and non-cancerous liver tissues (right, n = 123). G The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TCGA dataset. H Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TCGA dataset (n = 240). I Multivariate Cox regression analysis of the data from the TCGA dataset revealed that CCDC91 was an independent predictor of OS (n = 120). J The Kaplan–Meier analysis and log-rank test revealed the association of CCDC91 with the overall survival of HCC patients from TMA cohort (n = 123). K Multivariate logistic regression analyses for the associations of CCDC91 expression in HCC patients from TMA cohort (n = 80). Statistical analysis was performed using Student’s t test in ( C , D , E , and F ). Error bars represent the SEM. *, p < 0.05; **, p < 0.01; ***, p < 0.001.

    Article Snippet: HBV capture sequencing was conducted by MyGenostics (Beijing, China).

    Techniques: Sequencing, Immunohistochemistry, Staining, Expressing